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[Des-Arg9]-Bradykinin
CAS No. 15958-92-6
[Des-Arg9]-Bradykinin ( —— )
产品货号. M30110 CAS No. 15958-92-6
[Des-Arg9]-Bradykinin is a Bradykinin (B1) receptor agonist that displays selectivity for B1 over B2 receptors.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥346 | 有现货 |
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| 10MG | ￥562 | 有现货 |
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| 25MG | ￥1102 | 有现货 |
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| 50MG | ￥1649 | 有现货 |
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| 100MG | ￥2470 | 有现货 |
|
| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
生物学信息
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产品名称[Des-Arg9]-Bradykinin
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述[Des-Arg9]-Bradykinin is a Bradykinin (B1) receptor agonist that displays selectivity for B1 over B2 receptors.
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产品描述[Des-Arg9]-Bradykinin is a Bradykinin (B1) receptor agonist that displays selectivity for B1 over B2 receptors. (In Vitro):The B2 receptor mediates the action of bradykinin (BK) and lysyl-bradykinin (Lys-BK), the first set of bioactive kinins formed in response to injury from kininogen precursors through the actions of plasma and tissue kallikreins, whereas the B1 receptor mediates the action of [Des-Arg9]-Bradykinin (des-Arg9-BK) and Lys-des-Arg Arg9-BK, the second set of bioactive kinins formed through the actions of carboxypeptidases on BK and Lys-BK, respectively.
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体外实验The B2 receptor mediates the action of bradykinin (BK) and lysyl-bradykinin (Lys-BK), the first set of bioactive kinins formed in response to injury from kininogen precursors through the actions of plasma and tissue kallikreins, whereas the B1 receptor mediates the action of [Des-Arg9]-Bradykinin (des-Arg9-BK) and Lys-des-Arg Arg9-BK, the second set of bioactive kinins formed through the actions of carboxypeptidases on BK and Lys-BK, respectively.
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体内实验——
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同义词——
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通路GPCR/G Protein
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靶点Bradykinin Receptor
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受体Bradykinin (B1) receptor
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研究领域——
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适应症——
化学信息
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CAS Number15958-92-6
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分子量904.02
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分子式C44H61N11O10
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纯度>98% (HPLC)
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溶解度——
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SMILES——
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化学全称Sequence:Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
Leeb-Lundberg LM, et al. International union of pharmacology. XLV. Classification of the kinin receptor family: from molecular mechanisms to pathophysiological consequences. Pharmacol Rev. 2005 Mar;57(1):27-77.
产品手册
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[Des-Arg9]-Bradykini...
[Des-Arg9]-Bradykinin is a Bradykinin (B1) receptor agonist that displays selectivity for B1 over B2 receptors.
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Icatibant
缓激肽 B2 受体 (B2R) 的选择性和特异性拮抗剂，IC50 和 Ki 分别为 1.07 nM 和 0.798 nM。
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Bradykinin (1-7)
Bradykinin (1-7) is an amino-truncated Bradykinin peptide. Bradykinin (1-7) is a metabolite of Bradykinin, cleaved by endopeptidase.
